The 5-Second Trick For is sodium pentobarbital a controlled drug
The 5-Second Trick For is sodium pentobarbital a controlled drug
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Drug interactions: Most reports of clinically considerable drug interactions transpiring with the barbiturates have included phenobarbital.
Contraindicated (one)pentobarbital will reduce the level or effect of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the extent or effect of fludrocortisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will lower the extent or effect of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lessen the extent or effect of buprenorphine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will decrease the level or effect of cariprazine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Particular patient inhabitants: Dosage really should be lowered during the aged or debilitated since these clients might be far more sensitive to barbiturates. Dosage must be minimized for sufferers with impaired renal function or hepatic disorder.
pentobarbital decreases levels of elvitegravir/cobicistat/emtricitabine/tenofovir DF by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Could produce lack of virologic response and possible resistance.
pentobarbital will minimize the level or effect of ketoconazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.
pentobarbital will reduce the level or effect of donepezil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unfamiliar.
pentobarbital will decrease the extent or effect of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will lower the level or effect of mifepristone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. CYP3A4 inducers haven't been researched, coadministration not suggested by maker
pentobarbital will decrease the level or effect of pazopanib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Anticoagulants: Phenobarbital lowers the plasma amounts of here dicumarol (name Formerly used: bishydroxycoumarin) and causes a minimize in anticoagulant activity as calculated from the prothrombin time. Barbiturates can induce hepatic microsomal enzymes causing elevated metabolism and reduced anticoagulant reaction of oral anticoagulants (e.